GoldBio has a wide variety of analytical and organic reagents to ensure your research is accurate. For testing and classification purposes, we also offer a range of dyes, stains and indicators along with substrates and standards that will help you identify and analyze everything from biochemical interactions to bacterial classifications. In addition, our stock of pharmaceutical intermediates will help you build research grade molecules. All of these products are offered at the highest grade to ensure that you get the most accurate results.
Spartein is a class 1a antiarrhythmic agent sodium channel blocker from scotch broom. As a reagent it can be used to synthesize multiple different transformation catalysts and other molecules.
(-)-Arctigenin is a dibenzylbutyrolactone ligand found in the root of Arctium lappa L. It is an inhibitor of topoisomerase II, viral integrase including HIV-1 integrase, PAC-1, TNF-alpha, and nitric oxide secretion. Additionally, (-)-arctigenin displays anti-oxidative, anti-inflammatory, and anti-cancer properties. (-)-Arctigenin has been used in research on cosmetics and pharmaceutical products.
(S)-(+)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid is more commonly known as naproxen. It is a non-steroidal anti-inflammatory agent and non-selective inhibitor of cyclooxygenase (COX-1 and COX-2). Naproxen has been shown to decrease production of thromboxane B2.
1,2,3,4-Tetra-O-acetyl-β-D-glucuronic acid methyl ester has been used in various biochemical studies. It has been used to study the potential of water-soluble camptothecin glucuronide derivatives as a cancer prodrug monotherapy and antibody-directed enzyme prodrug therapy. Additionally, it has been used to assess the role of glycosylthio heterocycles in carbohydrates.
1,2-Benzoisothiazolin-3-one, sodium salt is an isothiazolinone biocine used in plants and as a preservative. Its mode of action is both fungicidal and microbicidal.
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine or DPPE is a phospholipid component of the cell membrane. It is used in membrane models and is part of the glycerophosphoethanolamine family. DPPE has been shown to cause competitive hydrogen bonding of amine groups with phosphate/carbonyl groups or water. Additionally, DPPE has been studied along with cholesterol, showing cholesterol’s ability to induce DPPE monolayer condensation when calcium ions are present.
1-O-Methyl-β-D-glucopyranoside is commonly used to study the specificity of yeast Saccharomyces cerevisiae in removing carbohydrates by fermentation. Additionally, it has been used to analyze alternansucrase acceptor reactions with methyl hexopyranosides.
10-Deacetyl baccatin III is an intermediate in the synthesis of the chemotherapeutic drug, paclitaxel (taxol). It is produced by and isolated from Taxus baccata. 10-Deacetyl baccatin III is an immiscible organic compound.
2,2’-Bipyridine is a metalloprotease inhibitor used as a reagent for the colorimetric determination of iron. It is a base used for oxidation-reductions indicators and to confirm the presence of ferrous iron in soils. Additionally, 2,2’-bipyridine is used in transition metal catalysis and aluminum-initiated polymerization. It is a high-affinity iron chelator and may inhibit iron-containing enzymes.
2,3-Dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) has a variety of applications. DDQ is a deprotection agent for ketals, acetals, and thioacetals. It is a useful electron transfer reagent for synthesis of quinolones and an oxidizing agent used to synthesize steroids. Additionally, DDQ is used with Ph3P to synthesize 1,2-benzisoxazoles.
2,4,6-Tris(2-pyridyl)-1,3,5-triazine or TPTZ is a triazine compound containing 3 pyridyl groups. It is commonly used as a reagent for the spectrophotometric determination of Fe(II) and total Fe. It can also be used to determine the amount of acetaminophen in samples through spectrophotometry.
2-Deoxy-D-galactose is a deoxy hexose that inhibits synthesis of glycoproteins in Influenza virus, such as hemagglutinin and neuraminidase, by blocking glycosylation. 2-Deoxy-D-galactose also inhibits the glycosylation of mammalian proteins involved in neurotransmitter release and synaptogenesis in the hippocampus. It has been used for isolating galactose permease mutants of Salmonella typhimurium and in the inhibition of glycolysis in Saccharomyces cerevisiae. It has also been used to isolate and elucidate the activity of a system for galactose uptake into E. coli.
2-Naphthyl caprylate is a chromogenic substrate for carboxylesterase
and lipase. 2-naphthol is released upon hydrolyzation. By simultaneous
coupling with a diazonium salt, the corresponding azo-dye is formed.
Naphthols can also be detected by fluorescence analysis, and can be
used in a colorimetric assay for the extracellular lipase of Pseudomonas fluorescent B52.
2-Nitrophenyl-β-D-galactopyranoside or ONPG is a chromogenic substrate for β-galactosidase. Upon hydrolysis, ONPG releases galactose along with a chromogenic yellow compound. Additionally, ONPG is a substrate useful for the determination of β-glucosidases.
3,5-Dichloro-2-hydroxybenzenesulfonic acid, disodium salt is a reagent used to produce peroxides when combined with 4-aminoantipyrine. It is also used in quantification of hydrogen peroxide through horseradish peroxidase-mediated conversion of itself and 4-aminoantipyrine to a colored product. Under this principle, it is used to determine uric acid in serum as oxidation of uric acid in a uricase-catalyzed reaction yields hydrogen peroxide.
