Description
Tested and Certified for in vivo imaging (See “Luciferin FAQ” in additional information)
Luciferin is a common bioluminescent reporter used for
in vivo imaging of the expression of luciferase. This water soluble substrate for the firefly luciferase enzyme utilizes ATP and Mg2+ as cofactors to emit a characteristic yellow-green emission in the presence of oxygen, which shifts to red light in vivo
at 37°C. Through the utilization of ATP, the reaction can be further
used to indicate the presence of energy or life in order to function as a
life-death stain.
Luciferin is a common reagent used throughout the biotechnology field and specifically for
in vivo imaging. Luciferase labeled tumor cells, stem cells
or infectious diseases are often inoculated into research animals such
as rats or mice for investigation. The injection of luciferin allows
for the real-time, noninvasive monitoring of disease progression and/or
drug efficacy in these model systems through Bioluminescence Imaging
(BLI).
Luciferin is also commonly used for
in vitro research, including luciferase and ATP assays, gene
reporter assays, high throughput sequencing and various contamination
assays.
Product Specifications:
D-Luciferin, Potassium Salt,
4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic acid potassium salt,
MOLECULAR BIOLOGY GRADE (Premium Pure)
Formula: C11H7N2O3S2K
MW: 318.42 g/mol
Color: Light yellow powder
Purity: >99% pure. (Quality verified by nine independent criteria including HPLC and FTIR.)
Storage/Handling: Store desiccated at -20°C. Protect from light.
PubChem Chemical ID: 44134804
