Description
Tested and Certified for in vivo imaging (See “Luciferin FAQ” in additional information)
Luciferin is a common bioluminescent reporter used for in vivo imaging of the expression of luciferase. This water soluble substrate for the firefly luciferase enzyme utilizes ATP and Mg2+ as cofactors to emit a characteristic yellow-green emission in the presence of oxygen, which shifts to red light in vivo
at 37°C. Through the utilization of ATP, the reaction can be further
used to indicate the presence of energy or life in order to function as a
life-death stain.
Luciferin is a common reagent used throughout the biotechnology field and specifically for in vivo
imaging. Luciferase labeled tumor cells, stem cells or infectious
diseases are often inoculated into research animals such as rats or mice
for investigation. The injection of luciferin allows for the
real-time, noninvasive monitoring of disease progression and/or drug
efficacy in these model systems through Bioluminescence Imaging (BLI).
Luciferin is also commonly used for in vitro research,
including luciferase and ATP assays, gene reporter assays, high
throughput sequencing and various contamination assays.
Product Specifications:
D-Luciferin, Sodium Salt monohydrate
4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic acid sodium salt
MOLECULAR BIOLOGY GRADE (Premium Pure)
Formula: C11H9N2O4S2Na
MW: 320.32 g/mol
Color: Light yellow powder
Purity: >99% pure (Quality verified by nine independent criteria including HPLC and FTIR.)
Storage/Handling: Store desiccated at -20°C. Protect from light.
PubChem Chemical ID: 23710675
