Description
| Description | AWL-II-38.3 is a highly effective inhibitor of EphA3, a receptor for ephrin-A. It demonstrates potent kinase inhibitory activity against EphA3 and does not show significant cellular activity against Src-family kinases or b-raf [1] [2]. |
| In vitro | AWL-II-38.3 fits to LIMK2 and LIMK1 ATP-binding and substrate-binding pockets [2] . |
| Molecular Weight |
469.42 |
| Formula | C23H18F3N5O3 |
| CAS No. | 1135205-94-5 |
Storage
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Solubility Information
DMSO: 65 mg/mL (138.47 mM),
Need ultrasonic
( < 1 mg/ml refers to the product slightly soluble or insoluble )
