Healthcare, pharmaceutical and industrial organizations rely on quality-assured prepared media every day
Maintaining cleanrooms and other aseptic areas to the most stringent regulations, plus validating sterility testing processes, requires quality assured prepared culture media. The EU GMP Annex 1 highlights an increasing need for organisations operating in pharmaceutical and medical device manufacture, and other industrial sectors, to reduce the risk of contamination wherever possible. Businesses that rely on clean room areas for their manufacturing will need to use prepared cultured media including poured media plates, bottled media, broth bags, ampoules – and perhaps even some bespoke media and accessories – to match the specific requirements of both organisation and facility. Discover more!
GlycoMatrix™ is a new division of bioWORLD. Using U.S. based manufacturing capability, GlycoMatrix™ has introduced a broad range of the most relevant lectins. The extensive portfolio contains lectin conjugates for the detection of specific glycoproteins & cancer biomarkers in histological applications, as well as separation and purification matrices, including Separopore® agarose beads, MagneZoom™ paramagnetic beads, and BlackPearl® magnetic Separopore® beads. GlycoMatrix™ lectins have become increasingly important tools in the molecular and cellular biology areas for studying carbohydrates, glycoproteins, and cancer biomarkers. Discover more!
Bioluminescence is the production and emission of light by a living organism. Bioluminescence occurs widely in marine vertebrates and invertebrates, as well as in some fungi, microorganisms and terrestrial invertebrates. Luciferin, the firefly substrate of luciferase, is a common reagent used throughout the biotechnology field. The injection of luciferin allows for the real-time, noninvasive monitoring of disease progression and/or drug efficacy in these model systems through Bioluminescence Imaging (BLI). Coelenterazine is a luminophore is the substrate for many luciferase enzymes, including Renilla reniformis, gaussia, and aequorins. It is commonly used to monitor reporter genes in BRET (Bioluminescence Resonance Energy Transfer), ELISA and HTS methods. Gold Biotechnology’s luciferin and coelenterazine are Proven and Published™ to ensure a quality reagent with optimal potential. Discover more!
IPTG is an analog of galactose that is nonmetabolizable and inactivates the lac repressor to induce synthesis of β-galactosidase in E. coli. The expression of cloned genes under the control of the lac operon is induced by IPTG. IPTG is often used in the induction of recombinant proteins, is a substrate for thigalactoside transacetylase and has been reported to induce penicillinase in bacteria. IPTG is commonly used in cloning procedures that require induction of β-galactosidase and is most often used with X-Gal for blue/white bacterial colony screening. GoldBio’s is most cost effective IPTG on the market, without sacrificing quality or purity. Gold Biotechnology IPTG is Proven and Published™ and is a better way to generate the experimental results you need while focusing your budget on the things that really matter. ORDER NOW!
TCEP (Tris (2-Carboxyethyl) phosphine Hydrochloride) is an odorless reducing agent suitable for protein applications and in the preparation for electrophoresis. TCEP is water soluble, is stable in a variety of solutions and is particularly useful in the labeling of cysteine residues with maleimides, preventing the cysteines from forming disulfide bonds. As a reducing agent, TCEP has many other desirable features, including: TCEP-HCl is stable in air. TCEP-HCl is odorless so reactions can be carried out on the bench without the need for a fume hood. TCEP-HCl is efficient and can be used to reduce disulfide bonds at low concentrations. TCEP-HCl may be used as a substitute for DTT at a final concentration of 50mM. ORDER NOW!
Oxidative stress & Antioxidants
Oxidative stress, as one of the most common types of toxicity, is defined by an imbalance between the generation of reactive oxygen species (ROS) and the ability of biological systems to detoxify ROS or its related damage. Many types of chemical, physical, and microbial agents can potentially induce oxidative-mediated stress in cells and tissues by damaging the biological components, including proteins, lipids, and DNA. Additionally, it has been proved that oxidative stress reactions can interfere with many essential biological processes such as phagocytosis (immunity and inflammation), cell respiration (mitochondria), metal metabolism, lipid synthesis, lysosomes, xenobiotic biotransformation of organic compounds and cellular signaling. Discover more!