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Introduction

Introduction

Hello, and welcome to the redesigned Goldbio.com, and to Shared Results, our new hub for discussion, research topics and news. You will notice some new features on our website, including an expanded search bar to help you find our products via chemical name, catalog...

Product Spotlight: Nourseothricin

Product Spotlight: Nourseothricin

Nourseothricin is an antimicrobial produced by the soil bacteria Streptomyces noursei and belongs to a subgroup of antibiotics that share a chemical structure called streptothricins (STs). Streptothricins are made up of a carbamoylated gulosamine molecule attached to...

Imaging and Tumor Growth

Imaging and Tumor Growth

We love taking a peek at open-access research articles, and we love sharing our finds with fellow readers even more. We recently came across an article on imaging and tumor growth from the University of Texas Southwestern Medical Center. The study described in the...

Troubleshooting: Purification of a Tagged Protein

Troubleshooting: Purification of a Tagged Protein

Purification of a tagged protein may seem like a pretty routine task. You express your protein of interest, lyse the cells, put the lysate through the resin, elute, and your freshly purified protein is ready for the world. Unfortunately though, this process can have...

Product Spotlight: Bialaphos

Product Spotlight: Bialaphos

Bialaphos is a tripeptide antibiotic naturally produced by a few species of the soil bacteria, Streptomyces. It is made up of two alanine residues and the glutamic acid analog phosphinothricin, also called glufosinate. Inside the cell, peptidases release the...

Are YOU Using Dual-Luciferase?

Are YOU Using Dual-Luciferase?

If there is one thing which always sparks our interest at GoldBio, it’s the novel methods and discoveries that proliferate in our biotechnology field! Take luciferase for example. Though this compound was detailed half a century ago and has been in increasing use in...

Product Spotlight: Coelenterazine

Product Spotlight: Coelenterazine

Coelenterazine is a naturally occurring substrate, or luciferin, for a diverse collection of luciferases. In the presence of molecular oxygen, the luciferase oxidizes coelenterazine, generating a high-energy intermediate and emitting blue light in the process (1)....

Product Spotlight: Rapamycin

Product Spotlight: Rapamycin

Rapamycin (Gold Biotechnology, R-101) is such a remarkable drug! It’s a macrocyclic triene antibiotic, an immunosuppressant, it has anti-cancer and anti-proliferative properties and, oh, by the way, it may also help increase your life-span. That’s an awful lot of...

Tryptophan Dreaming (on Turkey Day)

Tryptophan Dreaming (on Turkey Day)

Here in the States, we are all gearing up for that very special day of days: when the gravy lakes overflow their banks of mashed potatoes, when the cranberry sauce collides with grandma’s green bean casserole, the marshmellow-y goodness of the yams cascades over it...

Tetracycline Hydrochloride Quick Overview

Tetracycline Hydrochloride Quick Overview

It has been long believed that having a “sweet tooth” and eating too much sugar is a leading cause for type-2 diabetes. But we now understand that diabetes is a complicated disease, caused by a combination of genetic and environmental factors which doctors and...

Bonds for Science

Bonds for Science

The future state of scientific funding seems to have become a topic of concern lately, especially as talk of sequestration seeps from Washington, DC. Regardless of individual politics, the fact appears to be simple: there is going to be less money coming from the...

Reducing Agents (part 1 of 4) – Dithiothreitol

Reducing Agents (part 1 of 4) – Dithiothreitol

There are a number of reducing agents that are available at Gold Bio: DTT (dithiothreitol), DTE (dithioerythritol), L-glutathione (GSH) and TCEP (Tris (2-Carboxyethyl) phosphine hydrochloride). By definition, reducing agents are elements or compounds that donate an...

Troubleshooting: Protein Expression

Troubleshooting: Protein Expression

Last time on Troubleshooting, we covered Tagged Protein Purification, but what happens if your protein of interest isn’t being expressed in the first place!Induction of a bacterial protein should be pretty straightforward. You add your inducer to your culture, and...

Reducing Agents (part 2 of 4) – L-Glutathione

Reducing Agents (part 2 of 4) – L-Glutathione

Previously, we started discussing the function of various reducing agents. There are a number of reducing agents that are available at Gold Bio: DTT (dithiothreitol), DTE (dithioerythritol), L-glutathione (GSH) and TCEP (Tris (2-Carboxyethyl) phosphine hydrochloride)....

It Must Have Been the Mistletoe!

It Must Have Been the Mistletoe!

It’s Christmas time at Gold Bio! As the days count down to that perennial epic journey of one jolly, old elf, make sure you deck the halls with boughs of holly, rock around the Christmas tree, sing some yuletide carols by a fire and leave a peppermint stick for old...

Reducing Agents (Part 3 of 4) – DTE (dithioerythritol)

Reducing Agents (Part 3 of 4) – DTE (dithioerythritol)

Previously, we’ve been discussing the function of various reducing agents. There are a number of reducing agents that are available at Gold Bio: DTT (dithiothreitol), DTE (dithioerythritol), L-glutathione (GSH) and TCEP (Tris (2-Carboxyethyl) phosphine hydrochloride)....

Influenza Season

Influenza Season

Each year the flu kills 36,000 people and hospitalizes 200,000 more in the United States. All in all, about 20% Americans are affected by the flu each year. The flu kills roughly a quarter-million people worldwide each year and this year appears to be a bit worse....

Blue-White Screening

Blue-White Screening

For today’s blog post, we’re going to shine a spotlight on a widely used technique in the field of molecular biology, Blue-White screening. While this technique has been around for some time, it is still very important to researchers doing genetic engineering because...

His-Tag Metal Affinity Cations: What’s the difference again?

His-Tag Metal Affinity Cations: What’s the difference again?

Unless you’ve done the equivalent of a post-doc on his-tag protein purification, you have probably always wondered about the various metal cations available and what each one does for your purification needs. Today, we get to look into the sometimes-mysterious world...

GST-Tagged Protein Purification

GST-Tagged Protein Purification

There are a number of great methods in the researcher’s toolbox for protein purification. Along with the ever popular His-Tagged protein purification, there is also the choice of GST-tagged proteins. Glutathione S-transferase is a super family of enzymes that have...

Happy New Year!

Happy New Year!

The Chinese New Year (or Lunar New Year or Spring Festival) began yesterday. We want to extend special wishes to all of our Chinese readers and all of our other readers who celebrate this holiday. For those of you who do not know, Chinese New Year celebrations...

GoldBio Valentine’s Day

GoldBio Valentine’s Day

February 14th is celebrated as Valentine’s Day in the US. We mark the occasion by collectively giving flowers, chocolates, dinners and gifts to the special people in our lives. News agencies detail that American consumers dish out over $13 BILLION in various ways on...

Goldbio Video Reference Library

Goldbio Video Reference Library

Dear Readers,I am excited to announce that we are launching the Goldbio Video Reference Library today! As long as we've been selling our high-quality products, we've been hard at work in the lab using them too. Now we're turning our experience into something you can...