Description
| Description | Carbenicillin disodium (BRL-2064) is a broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant activity. |
| In vitro | In patients with cystic fibrosis, Carbenicillin (0.1μg/mL) exhibited no hypersensitivity drug reactions as measured by antibody levels. In chrysanthemums and TOBC, Carbenicillin (50 μg/mL) induced phytotoxicity in a concentration-dependent manner. |
| In vivo | Carbenicillin (125 mg/L) effectively suppresses the proliferation of soil bacteria, increases the volume of somatic embryos, and the number of somatic embryos per callus tissue. Within the callus tissue, Carbenicillin at concentrations of 250 mg/L to 500 mg/L can enhance the fresh weight of the tissue. At a higher concentration of 1 g/L, Carbenicillin reduces the germination frequency of leaf disc explants. Additionally, in vitro exposure of patients’ isolated leukocytes to Carbenicillin (0.1 g/ml) does not result in histamine release. |
| Synonyms | BRL-2064, Sodium carbenicillin |
| Molecular Weight |
422.36 |
| Formula | C17H16N2Na2O6S |
| CAS No. | 4800-94-6 |
Storage
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
H2O: 77 mg/mL (182.3 mM)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 60 mg/mL (142.06 mM)
