Description
| Description | Conteltinib (CT-707) is an enzyme inhibitor with antitumor activity targeting FAK, ALK, and Pyk2.Conteltinib exhibits significant inhibition of FAK, overcomes hypoxia-mediated sorafenib resistance in hepatocellular carcinoma through inhibition of YAP signaling, and can be used in advanced ALK-positive non-small-cell lung cancer and lymphoma. |
| Targets&IC50 | FAK:1.6 nM |
| Synonyms | SY-707, CT-707 |
| Molecular Weight |
635.82 |
| Formula | C32H45N9O3S |
| CAS No. | 1384860-29-0 |
Storage
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 20 mg/mL (31.46 mM),
Sonication is recommended.
