Description
| Description | Disitamab vedotin (RC48) is a cleavable antibody-drug conjugate (ADC) that combines a monoclonal antibody targeting human epidermal growth factor receptor 2 (HER2) with the cytotoxic agent Monomethyl auristatin E (MMAE). This compound effectively enhances antitumor immunity. |
| In vitro | The antibody part was a humanized monoclonal antibody targeting HER2, the small molecule toxin was monomethyl auristatin E (MMAE), a synthetic antineoplastic agent. A protease cleavable linker covalently attached MMAE to the antibody[2]. |
| Synonyms | RC48 |
| Molecular Weight |
N/A |
| CAS No. | 2136633-23-1 |
Storage
store at -20 ℃
Solubility Information
( < 1 mg/ml refers to the product slightly soluble or insoluble )
