Description
| Description | Fesoterodine ((R) Fesoterodine) is an orally active, competitive mAChR antagonist with pKi values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, respectively. It is used for the overactive bladder (OAB). |
| Targets&IC50 | M2 mAChR:7.7(pKi), M3 mAChR:7.4(pKi), M1 mAChR:8.0(pKi) |
| In vivo | Fesoterodine (0.01-1 mg/kg; i.v.) reduces the micturition pressure and increases bladder capacity and ICIs (intercontraction intervas) at the lowest dose tested of 0.01 mg/kg [3]. |
| Synonyms | (R) Fesoterodine |
| Molecular Weight |
411.58 |
| Formula | C26H37NO3 |
| CAS No. | 286930-02-7 |
Storage
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
Ethanol: 50 mg/mL (121.48 mM),
Sonication is recommended.
