Description
| Description | [Leu5]-Enkephalin acetate is an endogenous neuropeptide involved in nociception and an agonist of δ-opioid and μ-opioid receptors (Kis = 4.0 and 3.4 nM, respectively) |
| Targets&IC50 | δ-opioid receptor:4.0 nM(ki), μ-opioid receptor:3.4 nM(ki) |
| In vivo | [Leu5]-Enkephalin is found in the brain, the brainstem, and the spinal cord as well as in the peripheral nervous system. Leu-Enkephalin (1 mg/kg) decreases the visceromotor response to colon distension in a mouse model of visceral pain induced by colorectal distension[1]. |
| Synonyms | Leucyl-enkephalin, Leu-enkephalin, Leucine enkephalin |
| Molecular Weight |
555.63 |
| Formula | C28H37N5O7 |
| CAS No. | T7173L |
Storage
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Solubility Information
( < 1 mg/ml refers to the product slightly soluble or insoluble )
