Description
Description | m-PEG11-Br is a PEG-based PROTAC linker. m-PEG11-Br can be used in the synthesis of PROTACs. |
In vitro | PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight |
579.52 |
Formula | C23H47BrO11 |
CAS No. | 1258596-39-2 |
Storage
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Solubility Information
DMSO: 10 mM
( < 1 mg/ml refers to the product slightly soluble or insoluble )