Description
| Description | Mal-PEG5-Boc is a PEG-based PROTAC linker. Mal-PEG5-Boc can be used in the synthesis of PROTACs. |
| In vitro | PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| Synonyms | Mal-PEG5-COOtBu, Mal-PEG5-T-Butyl Ester |
| Molecular Weight |
445.5 |
| Formula | C21H35NO9 |
| CAS No. | 2250216-91-0 |
Storage
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Solubility Information
( < 1 mg/ml refers to the product slightly soluble or insoluble )
