Description
| Description | ML-210 is a selective RAS and covalent glutathione peroxidase 4 (GPX4) inhibitor(GPX4, EC50 : 30 nM), with anti-cancer activity |
| Targets&IC50 | GPX4:30 nM(EC50) |
| In vitro | ML210,the most potent and selective of these, displayed nanomolar potency in the primary screening cell line while maintaining selectivity similar to previously identified probes.?ML210 be highly useful in identifying pathways that can potentially be used for selectively inhibiting cancer cells[1]. |
| Synonyms | CID 49766530 |
| Molecular Weight |
475.3 |
| Formula | C22H20Cl2N4O4? |
| CAS No. | 1360705-96-9 |
Storage
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Solubility Information
DMSO: 11 mg/mL (23.14 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
