Description
| Description | N3-PEG8-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
| In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| Molecular Weight |
453.48 |
| Formula | C18H35N3O10 |
| CAS No. | 1343472-07-0 |
Storage
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
