Description
| Description | PBRM1-BD2-IN-7, a selective and cell-active inhibitor targeting the polybromo-1 (PBRM1) bromodomain, demonstrates inhibitory efficacy against PBRM1-BD2 with an IC50 value of 0.29 μM. This compound is utilized in cancer research. |
| In vitro | PBRM1-BD2-IN-7 (0, 0.1, 1, and 10 μM; 5 days) selectively inhibit growth of a PBRM1-dependent prostate cancer cell line. PBRM1-BD2-IN-7 has inhibitory activity for PBRM1-BD2 with IC50 value of 0.29 μM[1]. |
| Molecular Weight |
286.76 |
| Formula | C16H15ClN2O |
| CAS No. | 2819989-68-7 |
Storage
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 55 mg/mL (191.8 mM)
