Description
Description | Tavaborole (Kerydin) is a boron-containing small molecule antifungal agent with broad-spectrum activity against filamentous fungi, including both mold and yeast. |
In vitro | AN-2690 demonstrates a significant enhancement in efficacy, exhibiting an 8-fold increase in activity against both C. neoformans and A. fumigatus. It effectively inhibits cells expressing GlLeuRS-D444A, yet shows no inhibitory effect on cells expressing GlLeuRS or GlLeuRS-D444E. |
Synonyms | Kerydin, AN-2690 |
Molecular Weight |
151.93 |
Formula | C7H6BFO2 |
CAS No. | 174671-46-6 |
Storage
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 28 mg/mL(184.3 mM)