TCEP HCl

TCEP (Tris (2-Carboxyethyl) phosphine Hydrochloride) is an odorless reducing agent suitable for protein applications and in the preparation for electrophoresis. TCEP is water soluble, is stable in a variety of solutions and is particularly useful in the labeling of cysteine residues with maleimides, preventing the cysteines from forming disulfide bonds. As a reducing agent, TCEP has many other desirable features, including:

•TCEP-HCl is stable in air.
•TCEP-HCl is odorless so reactions can be carried out on the bench without the need for a fume hood.
•TCEP-HCl is efficient and can be used to reduce disulfide bonds at low concentrations.
•TCEP-HCl is selective for disulfides and does not react with other protein side chains.
•TCEP-HCl may be used as a substitute for DTT at a final concentration of 50mM.

Product Specifications
TCEP-HCl;
Tris (2-Carboxyethyl) phosphine Hydrochloride

Molecular Biology Grade
Protease Free

Formula: C₉H₁₅O₆P • HCl

MW: 286.65 g/mol

Storage/Handling: Store desiccated at -20°C.

PubChem Chemical ID: 2734570

• TCEP 50 g and 100 g ships as multiple 25 g units to qualify for a small quantity exception to hazardous fees.
• Due to hazardous goods restrictions, this product cannot ship by ground shipping to Canada or Mexico.