Description
| Description | Zingerone (Vanillylacetone) is a nontoxic methoxyphenol isolated from Zingiber officinale, with potent anti-inflammatory, antidiabetic, antidiarrhoeic, antilipolytic, antispasmodic and anti-tumor properties. Zingerone(Gingerone) alleviates oxidative stress and inflammation, down-regulates NF-κB mediated signaling pathways. Zingerone(Gingerone) acts as an anti-mitotic agent, and inhibits the growth of neuroblastoma cells. |
| In vitro | Vanillylacetone is similar in chemical structure to other flavor chemicals such as vanillin and eugenol. It is used as a flavor additive in spice oils and in perfumery to introduce spicy aromas. Fresh ginger does not contain vanillylacetone; cooking the ginger transforms gingerol, which is present, into vanillylacetone through a retro-aldol reaction. Vanillylacetone is likely the active constituent responsible for the antidiarrheal efficacy of ginger. [1] |
| Source |
| Synonyms | Gingerone, Vanillylacetone, NSC 15335 |
| Molecular Weight |
194.23 |
| Formula | C11H14O3 |
| CAS No. | 122-48-5 |
Storage
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
Ethanol: 36 mg/mL (185.3 mM)
H2O: 10 mg/mL (51.48 mM),
Heating is recommended.
DMSO: 50 mg/mL (257.43 mM)
