First there was the iPod, then the iPhone, the iMac and the iPad…now featuring iGLuc!
If you’re anything like me (geek that I am), every new technological device tends to get your blood pumping and invokes an involuntary reflex to reach for your wallet. That’s even truer for the ever-popular “i”-products which tend to grab our collective-geek attention...
Glowing Plants and Kickstarter- Where Science and Public Funding Meet
Earlier this month a very unique and very successful Kickstarter campaign wrapped up. If you haven’t heard of it by now, kickstarter.com is a crowd funding website where people like musicians, artists, or inventors can pitch an idea for say a new album, or an outdoor...
Triple Bioluminescense – Luciferin, Coelenterazine and now Vargulin!
Before, beside us, and above The firefly lights his lamp of love.”by Bishop Reginald HeberBioluminescence is one of the premier tools that scientists have in research, whether studying in vitro or in vivo. Few devices allow for the range, versatility, and ease of use...
Undergrads in the Lab
If you've been browsing around the blog, you might find this post (as well as the last few) to be a little different from the normal informative or product-related posts. Well I might as well introduce myself, I'm the summer intern and will be giving you a little...
Bioluminscence Imaging (BLI) in Cardiac Regeneration
ne upon a time, I had an art teacher who gave me some of the best advice I have ever received. As I was laboring over a small section of a painting that I had been working on for several days, struggling over and over to get that one spot just right, he had come up...
Undergrads in the Lab II
There are many perks to working in an undergraduate lab. You get to make great networking connections, work on different projects, and be a part of cutting edge research. I had a great project that worked on bone-marrow derived stem cells (MSCs) that we successfully...
Luciferin illuminates progression of Glioblastoma multiforme (GBM) cancer
In the world of cancer, in which the word ‘frightening’ takes on entirely new perspectives, perhaps none is more frightening than brain cancer. Although brain cancer is not one of the leading types of cancer per capita, the brain’s absence of pain receptors can hide...
Tuberculosis-Luciferase Reporter Gene
Tuberculosis is a common, and often lethal, infectious disease which has circulated since the dawn of mankind. It is caused by the bacteria, Mycobacterium tuberculosis; a small, aerobic, nonmotile bacillus, which tends to lodge in the pulmonary system and from where...
Getting Back Into the College Swing of Things
Summer is quickly coming to an end, which means that the start to the school year is just around the corner. This can be quite a stressful time for teachers and students alike, especially if you are just starting college or transferring to a new school. Luckily for...
Does My Chemical’s Purity Really Matter?
One of the questions we receive from time to time at GoldBio is whether purity really matters when it comes to chemicals. We can understand that question. There is a huge variety of “grades” with different purities available for almost every chemical on the market....
Gold Bio New Products
As more customers continue to turn to Gold Bio to provide high quality and affordable chemicals, we continue to strive to provide reagents that meet our stringent quality standards that we can bring to our customers at low prices. For the past few months we have...
Antibiotic Fall from Grace
It’s extremely well known that our antibiotics are failing us. Alexander Fleming noticed it from the very beginning. Improper use of antibacterial agents leads to improved bacterial resistance to the agent. Throughout the decades since Fleming’s discovery of...
Circumventing Antibiotic Resistance
Aminoglycosides are one of the largest and most common classes of antibiotics we use on a daily basis. The founding member of this group, Streptomycin, was discovered early in the golden age of antibiotics and was the first antibiotic found to be efficacious in...
Enhancing the Inhibition of Cancer Cells
Autophagy is a very complicated process when it comes to cancer. In general, autophagy isn’t complicated at all. It is a highly conserved process in which damaged or long-lived proteins and organelles can be removed from cells. Functioning through lysosomal machinery,...
The Hunt is Still on For New Antibiotics
A few weeks ago, we had a blog post about the issues we’re facing due to our overuse of specific antibiotics, namely Cephalosporins. The overuse of these and similar antibiotic compounds has resulted in selecting for a whole new breed of multi-drug resistant bacteria,...
Antibiotic Resistance Inherent in the Soil
All of our naturally derived antibiotics come from the ground, or more specifically the organisms that live in the ground. It’s estimated that there are more organisms living in just one square inch of soil than there are humans in the entire world. And we know and...
Antibiotic Agents from the Amazon!
The search for new antibiotics goes on and the accepted norm seems to be keeping our eyes narrowly focused on the bacteria that pervade our lives day in and day out. That’s a great idea, of course. Bacteria out number us probably along an order of 1 billion to 1. But...
Finding Alternatives to Antibiotics
Stepping back briefly from the antibiotic discussion on growing resistance and the veritable nose dive of new discoveries, I found that there are actually several alternative methods currently in research that are not only promising but may also change the way we look...
Antibiotics in the Wild
There are a lot of things that humans believe that they have invented or discovered that just isn’t true at all. When our ancestors were first contemplating the domestication of cattle or goats as a source of meat and milk, some ants had already been raising aphids...
The Development of New Antibiotics – Countdown to Midnight on the ARA* Clock
(* Antibiotic Resistance Apocalypse)Over the last several weeks, I’ve been discussing the greater concern over the increasing resistance of our current medicines and our lack of emerging antibiotics in the pharmaceutical industry. As I close out this month of blogs,...
The Response of IL1A in Cell Death
Necrosis is a very bad thing. I used to think that all cell death was bad, but that was before I began to understand the difference between apoptosis and necrosis. In its most basic form: Apoptosis = good cell death and Necrosis = bad cell death. That may be a little...
Delirious for Cytokines
What if cases of delirium or instances of delusions were only a symptom of an imbalance of inflammatory growth factors in your brain? What if the root cause for debilitating mental diseases, such as Alzheimer’s, were really grounded in the never-ending tug and pull...
Lost your Tail? It’s OK, just make sure you have plenty FGF2!
The field of regenerative limb research is nowhere near as populated as some of the other biological sciences, like cancer research or stem cell research, but there is a fundamental importance to learning all we can from the creatures who possess this wonderful trait....
The Association of Growth Factors in Obesity
Obesity is one of best covered, and at the same time worst covered, topic in the news. Rightly so, since nearly every person is somehow or another hyper-concerned about their weight. Do I weigh too much? Do I not weigh enough? Does my weight accurately reflect my...