Description
Description | 1,3-Dibromo-5,5-dimethylhydantoin is an alkyl chain-based PROTAC linker that can be used in PROTAC synthesis. |
In vitro | PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight |
285.92 |
Formula | C5H6Br2N2O2 |
CAS No. | 77-48-5 |
Storage
Powder: -20°C for 3 years | In solvent: -80°C for 1 year