Description
| Description | (1S,2S)-Bortezomib is an enantiomer of Bortezomib. Bortezomib is a reversible and selective inhibitor of the proteasome with a Ki of 0.6 nM for 20S proteasome. |
| Targets&IC50 | 20S proteasome(ki):ki:0.6 nM |
| In vitro | Bortezomib disrupts the cell cycle, induces apoptosis, inhibits NF-κB, and possesses anti-cancer capacity[1]. |
| Synonyms | Bortezomib |
| Molecular Weight |
384.24 |
| Formula | C19H25BN4O4 |
| CAS No. | 1132709-14-8 |
Storage
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Solubility Information
DMSO: 40 mg/mL (104.1 mM),
Need ultrasonic
( < 1 mg/ml refers to the product slightly soluble or insoluble )
