Description
Description | Carboxy-PEG4-sulfonic acid is a PEG-based linker commonly employed in PROTAC synthesis [1]. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight |
330.35 |
Formula | C11H22O9S |
CAS No. | 1817735-25-3 |
Storage
Powder: -20°C for 3 years | In solvent: -80°C for 1 year