Description
Description | Carboxy-PEG5-sulfonic acid, a PEG-based PROTAC linker, is utilized for the synthesis of PROTACs[1]. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight |
374.41 |
Formula | C13H26O10S |
CAS No. | 1817735-38-8 |
Storage
Powder: -20°C for 3 years | In solvent: -80°C for 1 year