Description
| Description | MS31 trihydrochloride is a potent, highly affinity and selective fragment-like methyllysine reader protein spindlin 1 (SPIN1) inhibitor. |
| Targets&IC50 | SPIN1 by AlphaLISA:77 nM , SPIN1:(kd)91 nM , SPIN1 by FP:243 nM |
| In vitro | MS31 trihydrochloride potently inhibits binding of trimethyllysine-containing peptides to SPIN1, displays high binding affinity, is highly selective for SPIN1 over other epigenetic readers and writers, directly engages SPIN1 in cells, and is not toxic to nontumorigenic cells[1]. |
| Synonyms | MS31 trihydrochloride |
| Molecular Weight |
450.83 |
| Formula | C20H30Cl3N3O2 |
| CAS No. | T12111L |
Storage
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Solubility Information
DMSO: 60 mg/mL (133.09 mM),
Need ultrasonic
( < 1 mg/ml refers to the product slightly soluble or insoluble )
