Biological Description Chemical Properties Storage & Solubility Information Description S-Methylisothiourea sulfate ((S)-Methylisothiourea sulfate) is a potent and selective inhibitor of iNOS and exerts beneficial effects in rodent models of septic shock[1]. In...
Biological Description Chemical Properties Storage & Solubility Information Description Esonarimod (KE-298) is an antirheumatic drug. In vitro The IC50 of Esonarimod is 117.5 μg/mL. In RAW264.7 cells, Esonarimod (KE-298) (10 to 300 μg/mL) suppresses the production...
Biological Description Chemical Properties Storage & Solubility Information Description Epiberberine chloride (Epiberberine (chloride)) is an alkaloid isolated from Coptis chinensis, acts as a potent AChE and BChE inhibitor, and a non-competitive BACE1 inhibitor...
Biological Description Chemical Properties Storage & Solubility Information Description S-MTC is a selective inhibitor of type I nitric oxide synthase. In vitro S-MTC (100?μM) is able to obviously reduce nitrite production (25.2±1.1?μM) as compared to Aβ1-42...
Biological Description Chemical Properties Storage & Solubility Information Description Guanabenz Acetate (Wytensin) is a specific agonist of adrenergic receptor. The pEC50 for α2a-adrenergic receptor, α2b-adrenergic receptor and α2c-adrenergic receptor is 8.25,...
Biological Description Chemical Properties Storage & Solubility Information Description GKT136901 (AK120765) is an inhibitor of NOX1/4.It acts as Selective and Direct Scavenger of Peroxynitrite In vivo GKT136901 is a novel NOX-1/4 inhibitor with potential...
Biological Description Chemical Properties Storage & Solubility Information Description Uric acid sodium, scavengers of oxygen radicals, is a potent and common antioxidant that helps maintain stable blood pressure and resist oxidative stress. Uric acid sodium,...
Biological Description Chemical Properties Storage & Solubility Information Description 4-Hydroxyflavanone is a natural product, shows full vasorelaxing effects In vitro 4′-hydroxyflavanone were evaluated for the inhibition of nitric oxide production in...
Biological Description Chemical Properties Storage & Solubility Information Description Nitrosoglutathione (GSNO) is an endogenous transnitrosation donor involved in S-nitrosation of a variety of cellular proteins. GSNO, an exogenous NO donor and substrate of rat...
Biological Description Chemical Properties Storage & Solubility Information Description Skp2 Inhibitor C1 (SKPin C1)(SKPin C1) is a specific small molecule inhibitor of Skp2-mediated p27 degradation. In vitro in vitro: T47D cells treated with C1 (5 μM for 16...
Biological Description Chemical Properties Storage & Solubility Information Description Ro 20-1724 (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1 μM....
Biological Description Chemical Properties Storage & Solubility Information Description VGX-1027 (GIT 27) is an isoxazole compound with various immunomodulatory properties. In vitro VGX-1027 enhances survival rates and ameliorates clinical and histopathological...
