Biological Description Chemical Properties Storage & Solubility Information Description ZM-241385 is a high-affinity antagonist ligand selective for the adenosine A2A receptor. Targets&IC50 A2AR:1.4 nM (Ki) In vitro ZM 241385 has high affinity for A2a...
Biological Description Chemical Properties Storage & Solubility Information Description Puerarin (Kakonein), also known as Kakonein, is a member of the class of compounds known as isoflavonoid C-glycosides. It is a 5-HT2C receptor antagonist. In vitro...
Biological Description Chemical Properties Storage & Solubility Information Description MEG hemisulfate (Mercaptoethylguanidine hemisulfate) acts as a highly potent and selective suppressor of inducible NO synthase (iNOS), demonstrating EC50 values of 11.5 μM for...
Biological Description Chemical Properties Storage & Solubility Information Description Ciclopirox (HOE296b) exerts its action by binding to and chelating trivalent cations, such as Fe3+ and Al3+, thereby inhibiting the availability of essential co-factors for...
Biological Description Chemical Properties Storage & Solubility Information Description YS-49 is an activator of PI3K/Akt (a downstream target of RhoA). In vitro In RAVSMC and RAW 264.7 cells, YS-49 (1-100?μM; 18 hours; ) concentration-dependently inhibits the...
Biological Description Chemical Properties Storage & Solubility Information Description Butein (2’,3,4,4’-tetrahydroxy Chalcone), a plant polyphenol, is isolated from Rhus verniciflua. It can inhibit the activation of protein tyrosine kinase, NF-κB and STAT3, and...
Biological Description Chemical Properties Storage & Solubility Information Description Flurbiprofen (dl-Flurbiprofen) is an anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal...
Biological Description Chemical Properties Storage & Solubility Information Description Edaravone (MCI-186)(MCI-186) is a potent new free radical scavenger used for the therapy of patients with acute brain infarction. In vitro Edaravone significantly improves...
Biological Description Chemical Properties Storage & Solubility Information Description Phloretin (NSC-407292) is a well-known inhibitor of eukaryotic urea transporters, blocks VacA-mediated urea and ion transport. Phloretin is a dihydrochalcone, a type of natural...
Biological Description Chemical Properties Storage & Solubility Information Description Agmatine sulfate (Agmatine sulfate salt) is a bioactive metabolite of the arginine amino acid. It exerts modulatory action at multiple molecular targets, such as...
Biological Description Chemical Properties Storage & Solubility Information Description 3-Nitro-L-tyrosine (3-Nitrotyrosine) is the major product from the spontaneous reaction of peroxynitrite with tyrosine. Formation of nitrotyrosine can indicate the formation of...
Biological Description Chemical Properties Storage & Solubility Information Description 5-Aminosalicylic Acid (5-ASA) is an anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the...
