Description
Overview
Product name |
Recombinant Human Biglycan/BGN Protein |
Catalog No. |
RP00141 |
Description |
Recombinant Human Biglycan/BGN Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Asp38-Lys368) of human Biglycan/BGN (Accession #NP_001702.1) fused with a 6×His tag at the C-terminus. |
Purity |
> 80% by SDS-PAGE. |
Endotoxin |
< 0.1 EU/μg of the protein by LAL method. |
Formulation |
Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation. |
Species |
Human |
Background
Biglycan, also known as PG I, is a secreted chondroitin/dermatan sulfate proteoglycan in the small leucine-rich proteoglycan (SLRP) family.The protein is plays a role in bone growth, muscle development and regeneration, and collagen fibril assembly in multiple tissues. This protein may also regulate inflammation and innate immunity. Additionally, It may contribute to atherosclerosis and aortic valve stenosis in human patients.
Product information
Synonym |
DSPG1; PG-S1; PGI; SLRR1A |
Expressed Host |
HEK293 cells |
Tag |
C-6×His |
Swiss-Pro |
P21810 |
Gene ID |
633 |
Usage guide
Storage |
Store the lyophilized protein at -20°C to -80 °C for long term.After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week. |
Reconstitution |
Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. |